Does the Abbott system do what PEB does in a different way?
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Remember the Darling definition of successful commercialisation is 'getting a product to market'
Enduring sales and profitability is not part of that equation
I'm allowed to say that because not that long ago I put real cash into the business
Soooooo....it was BFG who did some digging...before being banNEd--------I think we are going to call him ''Banned on the run''
Well done Skid you’ve highlighted the importance of game changing disruptive technologies, and Uroysion have done very well indeed to flip FGFR3 onto others right about now;
A contributing reason for them doing so will undoubtedly be the pending Pacific Edge study, presently underway, that will directly compare the performance of Uroyvision with Cxbladder.
As I understand, it is a very similar study to the one Pacific Edge conducted to demonstrate the superiority of Cxbladder over Alere’s NMP22. The results of this study are due quite soon as I’m aware.
One of the challenges for any prospective competitor is that they really do need to demonstrate a quantum leap in process detection. Especially in the very early stages of tumor detection where the big benefits lie for patients, where the bulk of tests are performed, and where the big prospective commercial gains are possible.
Most importantly are the Tis, Ta, T1, T2 and T3 early stages of cancer, these are the ones, where if detected, then your chances of recovery as a patient still remain prospective.
As one can see from the table we all know below, it is really very hard indeed for any competitor to compete with the 100% sensitivity that Pacific Edge offer, and clinicians may well choose a product with 100% sensitivity over one that is less accurate as lives are literally in their hands.
I think some really do under estimate just how competitive these Pacific Edge products really are likely to be and just what a leap they represent as a disruptive technology.
Good luck Abbot, you have bought an aging dog.
Attachment 7041
Was'nt really me --I just brought it into the light of day so was'nt guessing games any more
In this article it looks like they have a bit of a jump on most competitors if the second illustation is anything to go by--but of course CX is not on there so its obviuosly not the full picture
https://lsconnect.thomsonreuters.com...le-biomarkers/
PS-just because i have run with another outfit doesnt mean i dont wish any KIWI company well--Its damn frustrating they are not even included in the illustration.
Glad I made my money on PEB when it suddenly rocketed, which seems so long ago now, so I can view this thread, with its strutting ego's and cryptic innuendo as entertainment and with bemused interest.
Otherwise, why would you
(merriam-webster.com/dictionary/bemuse
to cause to have feelings of wry or tolerant amusement)
Abbott:
Activating FGFR3 gene mutations are seen in about 70% of low-grade and 15 to 20% of high-grade bladder cancer cases, making them useful biomarkers to assist in early detection.
Pacific Edge:
- Detected 100% of T1-T3, Tis and upper tract tumours.
- Detected 97% of high-grade tumours.
- Detected 68% of Ta tumours as compared to cytology at 35%.
- Distinguished between low grade Ta tumours and other detected urothelial carcinomas with a sensitivity of 91% and specificity of 90%
No comment
There have been some very good postings by the likes of Snapiti questioning and commenting on PEB's commercialization strategy, and why PEB is failing to get real sales traction out there.
Issue here is that the PEB bulls simply do not want to know.
A classic example is Snapiti questioning why at this stage of the sales and commercialization cycle is PEB resorting to user programs to try and convert urologists to use CxBladder. Is this really part of PEB's commercialization strategy from day 1 or is it a case of backtracking in the absence of sales? The evidence from PEB's presentations point towards a backtrack.
Meanwhile, PEB bulls think that other players with existing tests are sitting still?
The move by Abbott is an example of them upping their game to improve their test(s) and entrench their market position. Snapiti has alerted to others who are upping their game as well.
$14m left in PEB's bank as at 30 September 2014 to take on the likes of Abbott with their established product, distribution network and billions of dollars at their disposal.
Cash burn of $1m to $1.5m a month - will there be enough actual sales before the cash runs out? You can only provide free tests and support user programs for so long.
And it's not like PEB is racking in the cash from sales made - debtor level on the balance sheet is higher than sales!!!!!! First time I have seen such a situation many years of analysing balance sheets.
"Tens of thousands of tests" and the Chairman selling shares after that - that was the give away for me that PEB is not meeting sales target as far as my initial assessment was concerned.
Subsequent to that, there are obviously other information which reinforces my perception (concession to you - my perception).
Competitors, suppliers, customers etc - that's who I talk to besides the companies i analyse.
Oct 2013 PEB signs up three major providers four months after release to market in US
Dec 2013 Infamous" tens of thousands" statement contained in ODT report
No comment
7.48 minerbarejet posts facts
7.49 Balance amends post to include chairman selling shares.
8.15 Balance posts a reply to himself.
no comment
Thanks for the prompt about the Chairman selling.
Forgot to include it first time but since you provided the prompt with your timeline post, I included it. Thanks again!
27 March 2012 - "Labtests exclusive sales for CxBladder".
30 May 2013 - "Mid Central DHB first to use CxBladder"
10 Sep 2013 - "CxBladder excels in NZ".
2 Oct 2013 - "Agreement with Choice makes CXBladder available to 14 million Americans".
16 Oct 2013 - "Agreement with Fedmed makes CxBladder available to an additional 40 million Americans" etc etc etc.
18 Oct 2013 - "First commercial sale for CxBladder in US"
22 Oct 2013 - "Agreement with Stratose gives access to 8.6 million Americans".
28 Dec 2013 - "SEVERAL tens of thousands of tests in 2014".
7 Mar 2014 - "Chairman sells shares".
10 Mar 2014 - "CEO sells shares".
Did I miss the clarification by PEB to the "SEVERAL tens of thousands of tests"? Please put in as appropriate.
7.48 minerbarejet posts facts
7.49 Balance amends post to include chairman selling shares.
8.15 Balance posts a reply to himself.
8.28 Minerbarejet posts timeline
8.49 Balance thanks Minerbarejet for posting a timeline at 8.28 that prompts him to amend his post to include "chairman selling shares" at 7.49
no comment
The development to date for those who are just joining the thread.
http://www.clpmag.com/2015/01/abbott...cer-biomarker/
"Abbott currently offers the only FDA-approved urine-based molecular test for bladder cancer, UroVysion, which is included in the National Comprehensive Cancer Network and European Association of Urology guidelines.
The FGFR3 mutation analysis assay will be available in early 2015. Abbott is also in the process of developing reagents for further studies, and is exploring collaborations with pharmaceutical companies to leverage the FGFR3 test as a companion diagnostic for emerging bladder cancer therapies."
For those new to the thread.....
and of far more consequence than the recent dramatic EXPOSE by the resident cock-teasers on this thread .....
the Crusaders lost 20/10 to the Rebels:eek2::eek2: ......jesus wept
I'm more worried by Carter's left leg injury, than Abbott, Costello and who-ever else has just been sold a pup of a product.
Could someone tell me who is the institution on the bid every closing auction please. Balance, is it you?
Oh, let me know when you are back off the bench
There are several other tests in the market place, hardly new news really, some of those have been available for 10 years now, some might even sell a few tests.
There are some that are in development too, but unless they can offer the same disruptive tech with 100% sensitivity within the key critical Tis, Ta, T1, T2 and T3 tumor stages, then they won’t be as good as Cxbladder(detect), it’s not easy equalling or bettering 100%, unless you think 101% is actually possible.
There are no other such test products presently available within the market, even if there was another in development at present, it then takes at least two, probably more, years to work through clinical trials and regulatory approvals to reach a commercial launch.
Pacific Edge already have two commercial test products and will have four commercial products by that time and are likely to be busy saturating the market with them, quite a barrier to entry even if others can do 100% too.
PEB should probably be well on their way to achieving their humble goal of achieving a 10% market share by then, quite an understated goal IMO, but perhaps in a couple of years another might come along with an equally good test and claim their own 10% of the market, who knows, it’s a big enough sand pit.
As for Abbot, they’ve bought very old and dated tech, and perhaps they will sell a few tests to suckers.
I’ll be happy to explain why their test will never really sell much, there is another really very good reason for that ?
Apologies for the ramble, just trying to better clarify for those new to Pacific Edge.
kind regards to all, Mac